Effect of Viagra on Male Health: out Complications while ED Treatment.

When Side Effect Afforded a Good Profit

Viagra is kind of the most well-known medical preparation in the world that is used to cope with signs of erectile dysfunction.

Effect of Viagra on Male Health: out Complications while ED Treatment.The history of its advent is rather interesting. In theory, Viagra had to become the medication for cardiovascular diseases. However, during clinical investigations its stimulant effect on male erection was found out. Pharmaceutical management team considered this unexpected side effect to be more valuable than treatment of heart diseases. Finally, Viagra appeared in pharmaceutical market as a medication for erectile dysfunction treatment. It happened more than 20 years ago, but it is still extremely popular with men with erectile problems.

How does it Work?

The cardinal active moiety of Viagra is Sildenafil. This medicinal component has a vasorelaxant action. This action expands mostly on distal vessels, including vessels in the external male genital organs. As a result, intake of Viagra enhances blood stream into cavernous penis bodies that causes an erection. But it should be noted that it can’t appear without a sexual arousal. The vasodilative effect happens thanks to selective inhibition of phosphodiesterase, which in its turn, leads to elution of active nitric oxide. This very element eases blood vessels thus boosting circulation of blood.

The medication is quickly absorbed into the blood. Its maximum concentration in blood Sildenafil reaches in 30-120 minutes. Oral bioavailability of the drug is 41 percent that is considered to be a fairly high rate. It means the amount of substance that is absorbed from the whole pill in the stomach.

Rules for Viagra Intake

  • Effect of Viagra on Male Health: out Complications while ED Treatment.You should take Viagra pill nearly 60 minutes before coitus;
  • Its action lasts for about 4 hours. It means that you can have sex so many times you want but only within this period;
  • Never overdose Viagra;
  • You may take Viagra pills every day or just right before intercourse. In both cases, the dose should be different. You should discuss with your doctor the desired frequency of Viagra intake; it helps him to put on an adequate dose;
  • Increase or decrease in dose is made by efficacy and tolerability;
  • Viagra pills are prescribed only after a medical check by an urologist and when medical tests are done;
  • The pill should be taken no more often than once a day;
  • It’s better to remember that fatty food and alcohol downregulate the Viagra absorption and the pill may be useless.

Mistakes of Viagra Intake, which may Costs Lives

There exist nitrates that refer to a group of medications for the treatment of cardiovascular diseases. The most well-known one is nitroglycerin. Cotreatment of Viagra and nitroglycerin causes a drop in blood pressure and inadequate blood supply of the brain. There are lots of recorded cases, when cotreatment of these meds kills death.

Please be aware that if a person has heartache after the intake of Viagra pill, it’s highly prohibited to give him nitroglycerine. Nitrate taking is banned a day before and a day after Viagra administration.

Viagra overdosage may cause a hyper erection (priapism), which doesn’t go away even after coitus. Priapism is rather dangerous to health and demands operative treatment.

Contraindications

Viagra intake can be unsafe or demands underdosing in the following health disorders:

  • Congenital or acquired abnormalities of penis anatomical organization;
  • Underlying risk for priapism;
  • Any blood diseases;
  • Attack of peptic ulcer of the digestive tract;
  • Hepatic disorders with its dysfunction;
  • Cardio-vascular diseases, etc.

At any rate, before taking Viagra, don’t forget to visit a doctor. Even you’re absolutely sure in your absolute health, only medical checks and tests are able to reveal your real physical condition.

 

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